Pareto-optimal balancing conflicting objectives in genome subgroup analysis.
AVAtar is a readily usable standalone software for analysis and visualisation of alteration data. AVAtar features interactively customizable alteration plots, extensive data import capabilities and a multi-objective optimization algorithm to find alteration patterns, e.g. gene sets with mutually exclusive alterations or small gene sets with high sample coverage.
The software is available at
Our paper "Unraveling the Molecular Tumor-Promoting Regulation of Cofilin-1 in Pancreatic Cancer" has been published in MDPI Cancers.
Our paper "Implementing FAIR data management within the German Network for Bioinformatics Infrastructure (de.NBI) exemplified by selected use cases" has been published online first in Briefings in Bioinformatics.