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Medical Systems Biology

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AVAtar

Pareto-optimal balancing conflicting objectives in genome subgroup analysis.

AVAtar is a readily usable standalone software for analysis and visualisation of alteration data. AVAtar features interactively customizable alteration plots, extensive data import capabilities and a multi-objective optimization algorithm to find alteration patterns,  e.g. gene sets with mutually exclusive alterations or small gene sets with high sample coverage.

The software is available at

https://github.com/sysbio-bioinf/avatar

Latest News

Our paper "Awakening the HSC: Dynamic Modeling of HSC Maintenance Unravels Regulation of the TP53 Pathway and Quiescence" has been published in Frontiers in Physiology.

 

Our review article "Concepts in Boolean Network Modeling - What Do They All Mean?" has been published in Computational and Structural Biotechnology Journal.