Medical Systems Biology

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Joint research projects

  • BIU-Project (Boehringer Ingelheim Ulm University BioCenter): 
    • Project N7: "Diagnostic role and predictive value of cyclic nucleotides in neuropsychiatric co-morbidities of Alzheimer’s disease"
  • Symbol-HF (BMBF, eMed): "Systems Medicine to dissect the Biology of Heart Failure"
  • SFB 1074(DFG): "Experimental Models and Clinical Translation in Leukemia"
    • Project Z1: "Parallel Algorithms for Robust Clustering, Classification, and Visualization"
  • CAM-PaC(European Comission, FP7): "Integrative Analysis of Gene Functions in Cellular and Animal Models of Pancreatic Cancer"
    • WP10: "Data Integration and Modeling"
  • SyStaR(BMBF, GerontoSys 2): "Molecular Systems Biology of Impaired Stem Cell Function and Regeneration during Aging"
    • Research Group Kestler
    • Research Group Senior PI (provisional)
    • Research Group Junior PI (provisional)
  • Genomics Core Facility, Ulm University
    • HAK is coordinator of bioinformatics
  • International Graduate School in Molecular Medicine, Ulm University
    • HAK is member of the PhD Committee
 

Research Training Projects

  

  • Research Training Group 2254: "Heterogeneity and Evolution in Solid Tumours" (HEIST):
    • Project A2: "Systems biology of tumour evolution: Estimating partial orders from omics data"
    • HAK is co-director of HEIST

 

Finished joint research projects


  • NGFN-Plus (BMBF): "Translational Genome Research Network in Pancreatic Cancer"
    • Project TP11B: "Molecular Diagnosis of Pancreatic Cancer"
  • SFB 518 (DFG): "Inflammation, Regeneration and Transformation in the Pancreas"
    • Project C05: "Robust Algorithms for Clustering and Classification of Pancreatic Cells and Tissues"

Latest News

 

Congratulations to Dr. Silke Werle for winning the 1st Prize with her pitch at the 1. Science Day held by ProTrainU. 

 

Our paper "Reconstructing Boolean network ensembles from single-cell data for unraveling dynamics in the aging of human hematopoietic stem cells" has been published in the Computational and Structural Biotechnology Journal.

 

The position paper "Is there a role for statistics in artificial intelligence" has been published online first in Advances in Data Analysis and Classification.

 

Our paper "Corona Health - A Study- and Sensor-Based Mobile App Platform Exploring Aspects of the COVID-19 Pandemic" has been published in the International Journal of Environmental Research and Public Health.

 

Our paper "Patient empowerment during the COVID-19 pandemic: Ensuring safe and fast communication of test results" has been published in the Journal of Medical Internet Research.

 

Our paper "Perspective on mHealth Concepts to Ensure Users’ Empowerment–From Adverse Event Tracking for COVID-19 Vaccinations to Oncological Treatment" has been published in IEEE Access.

  

Our report protocol "Digitalization of adverse event management in oncology to improve treatment outcome—A prospective study protocol" has been published in PLoS One.

 

We are happy we could contribute to Beutel et al (2021) "A prospective Feasibility Trial to Challenge Patient-Derived Pancreatic Cancer Organoids in Predicting Treatment Response" published in MDPI Cancers.