Medical Systems Biology

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Einführung in die Bioinformatik(Informatik/ Mathematische Biometrie)

Dozent: Prof. Dr. Hans A. Kestler
  Prof. Dr. Enno Ohlebusch
  Dr. Karlheinz Holzmann
  mit M. Sc. Lea Siegle








Vorlesungsbeginn ist am 16.10.2019

Die Besichtigung der Core Facility Genomics findet am 22.01.2020 statt. Treffpunkt ist um 8:30 in O27, 123.


*NEU* Die Klausureinsicht für die Nachklausur findet am 26.06.2020 von 10-11 Uhr in O28/2001 statt. Bitte beachten Sie, dass Sie den Raum nur einzeln betreten dürfen und auf den Laufwegen der Uni sowie während der Einsicht immer einen Mund-Nasen-Schutz tragen und 1.5m Abstand zu anderen Perspnen halten müssen.



Mittwochs 08:30 - 10:00 Uhr, O27, 123


Freitags 14:00 - 16:00 Uhr, O27, 121, alle zwei Wochen

Die Übung, die am 31.01.2020 stattfinden sollte, wird auf den 07.02.2020 verlegt.




Biologische Grundlagen (I/II)

Biologische Grundlagen (II/II)

Datenbanken und Alignments


Next Generation Sequencing





Übungsblatt 1

Übungsblatt 2

Übungsblatt 3

Übungsblatt 4

Übungsblatt 5

Übungsblatt 6

Übungsblatt 7








Erster Termin: 25.02.2020, 10:00-12:00 Uhr, O27/H20

Zweiter Termin: 19.06.2020, 08:00-11:00 Uhr, O27/H20

Job Openings

Wissenschaftlicher Mitarbeiter (m/w/d) 


Latest News


  1. Our paper "Prediction of resistance to bevacizumab plus FOLFOX in metastatic colorectal cancer-Results of the prospective multicenter PERMAD trial" has been published in PLoS One.


  2. "Introducing a machine learning algorithm for delirium prediction—the Supporting SURgery with GEriatric Co-Management and AI project (SURGE-Ahead)has been published in Age and Ageing.

Our paper "Segmentation-based cardiomegaly detection based on semi-supervised estimation of cardiothoracic ratio" has been published in Scientific Reports.


"Prospective study validating a multidimensional treatment decision score predicting the 24-month outcome in untreated patients with clinically isolated syndrome and early relapsing–remitting multiple sclerosis, the ProVal-MS study" has been published in Neurological Research and Practice.


Our paper "GatekeepR: an R shiny application for the identification of nodes with high dynamic impact in boolean networks" has been published online first in Bioinformatics.


Our paper "The Necessity of Interoperability to Uncover the Full Potential of Digital Health Devices" has been published in JMIR Medical Informatics.


"Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients" has been published in npj Precision Oncology.


Our paper "AMBAR-interactive alteration annotations for molecular tumor boards" has been published in Computer Methods and Programs in Biomedicine.


"A protocol for the use of cloud-based quantum computers for logical network analysis of biological systems" has been published in STAR Protocols.


Our paper "A systems biology approach to define mechanisms, phenotypes, and drivers in PanNETs with a personalized perspective" has been published in npj systems biology and applications.


"Supporting SURgery with GEriatric Co-Management and AI (SURGE-Ahead): A study protocol for the development of a digital geriatrician" has been published in PLoS One.


"Self-Assessment of Having COVID-19 With the Corona Check Mhealth App" has been published in IEEE Journal of Biomedical and Health Informatics.

Our first quantum computing paper "Leveraging quantum computing for dynamic analyses of logical networks in systems biology" has been published in Patterns.