Medical Systems Biology

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Bioinformatics and Systems Biology (MolMed)

Coordinator: Prof. Dr. H. A. Kestler

Code: MOME.Ma1002

 


Announcement:

Start of lectures:

Tuesday, 22.10.2019 (14:00 - 16:00)

 

Room changes:

Thursday, 24.10.2019 (16:00 - 18:00): O29, 3004

Tuesday, 31.10.2019 (14:00 - 16:00): O29, 3005/3006

Thursday, 28.11.2019 (14:00 - 16:00): O23, 2609/10

 

Lectures:

Tuesday (14:00 - 16:00): seminar room surgical clinic 3.391 

Thursday (14:00 - 16:00): O23, 2611 

 

Exercises:

Thursday (16:00 - 18:00): O29, 3005/3006

 

Exam:

The post-exam review will take place on 11.02.2020 (12:00-13:00) in room O29/2003.


Friday, 07.02.2020 (10:00 - 12:00): Hörsaal Chirurgie (Lecture Hall Surgery)

 

Slides:

Introduction

Signalling

Epigenetics

Programming with R and Bioconductor

Multivariate Statistics

Data Mining

High throughput technologies

Mass spectrometry and Proteomics - basics

Bioinformatics in MS based qualitative and quantitative proteomics

Mass spectrometry and Proteomics - NewDrugs

Sequence Analysis

Sequence Analysis - Manuscript

Simulation and modeling

Mathematical analysis of cell function

Boolean Networks

Qualitative Models Extensions

Quantitive Models

Exercise sheets:

Exercise sheet 1

Exercise sheet 2

Exercise sheet 3

Exercise sheet 4

Exercise sheet 5

Exercise sheet 6

Exercise sheet 7

Exercise sheet 8

Additional material:

Time table

R Cheat sheet

Exercise sheet 1: data_Sha_64.txt

Exercise sheet 2: multivariate_statistics.RData

Exercise sheet 2: knn.Data.RData

Exercise sheet 4: Exercises-2019.mgf

Latest News

 

Our paper "A systems biology approach to define mechanisms, phenotypes, and drivers in PanNETs with a personalized perspective" has been published in npj systems biology and applications.

 

"Supporting SURgery with GEriatric Co-Management and AI (SURGE-Ahead): A study protocol for the development of a digital geriatrician" has been published in PLoS One.

 

"Self-Assessment of Having COVID-19 With the Corona Check Mhealth App" has been published in IEEE Journal of Biomedical and Health Informatics.


Our first quantum computing paper "Leveraging quantum computing for dynamic analyses of logical networks in systems biology" has been published in Patterns.

 

Our paper "Unsupervised domain adaptation for the detection of cardiomegaly in cross-domain chest X-ray images" has been published in Frontiers in Artificial Intelligence.

 

  1. "The HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination" has been published online first in the British Journal of Cancer.

 

"Vaccine Side Effects in Health Care Workers after Vaccination against SARS-CoV-2: Data from TüSeRe:exact Study" has been published in Viruses-Basel.

 

"PREDICT-juvenile-stroke: PRospective evaluation of a prediction score determining individual clinical outcome three months after ischemic stroke in young adults – a study protocol" has been published in BMC Neurology.

 

Our paper "Federated Electronic Data Capture (fEDC): Architecture and Prototype" has been accepted for publiaction in the Journal of Biomedical Informatics.

 

Our paper "Efficient cross-valdation traversals in feature subset selection" has been published in Scientific Reports.

 

Our paper "CANTATA - prediction of missing links in Boolean networks using genetic programming" has been published in Bioinformatics.

 

Our paper "Interaction Empowerment in Mobile Health: Concepts, Challenges, and Perspectives" has been published in the Journal of Medical Internet Research mhealth and uhealth.

 

Our paper "Identification of dynamic driver sets controlling phenotypical landscapes" has been published in the Computational and Structural Biotechnology Journal.