The rapid development of molecular biology has given rise to an increasing demand in computational and mathematical approaches to analyze and understand the resulting data. In particular, advanced methods from Bioinformatics are required to extract and investigate the essential information from high-throughput experiments, such as microarrays or Next Generation Sequencing. The emerging field of Systems Biology provides formal approaches to modeling and simulating regulatory processes in biological systems.
The research of our group is at the interface of computer science, statistics and life sciences and covers the following main aspects:
Our paper "A Boolean Network of the Crosstalk Between IGF and Wnt Signaling in Aging Satellite Cells" has been published in Plos One.
Our paper "Long-lived rodents reveal signatures of positive selection in genes associated with lifespan" has been published in Plos Genetics.