Medical Systems Biology

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An R package for multi-objective parameter selection for classifiers: TunePareto R package


McKmeans: A highly efficient multi-core k-means algorithm for clustering extremely large datasets.


An R package that analyzes cluster alternatives based on multi-objective optimization of cluster validation indices: MOCCA R package


An R package for the generation, reconstruction, simulation and analysis of Boolean networks: BoolNet R package

HCMV drug resistance mutations

A new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes: HCMV drug resistance mutations


An open-source Java program for visualizing genomic abnormalities: IdeogramBrowser Software


An open-source Java program for drawing area proportional Venn/Euler diagrams: VennMaster Software


A Microsoft Excel add-in that visualizes gene expression ratios. The software is freely available upon request.

MCGH Analyzer

Software to analyze array CGH data with direct GPR import (Microsoft Excel add-in, Windows): MCGH Analyzer Software.


Perl program to create receiver operator charateristic (ROC) curves:


A document-centered environment for simulation and visualization of algorithms: Vital


Structural RNA alignment by multi-objective optimization: RNA-Pareto


Visualization of Ant Colony Optimization (contributed by Michael Grönert): Swarm


Swat is a java commandline software based on dynamic programming to calculate optimal local alignments of DNA/ RNA sequences and protein sequences.

RNASeq Count Analyzer

Differential expression analysis for sequence count data: RNASeq Count Analyzer


Clojure Framework for parallelization: Sputnik


TraqBio is a intuitively useable and a readily implementable open-source web application for progress tracking in core units. Its main intention is the communication of projects status between a core unit and its users: Source and Documentation

Latest News

Our paper "A Boolean Network of the Crosstalk Between IGF and Wnt Signaling in Aging Satellite Cells" has been published in Plos One.

Our paper "Long-lived rodents reveal signatures of positive selection in genes associated with lifespan" has been published in Plos Genetics.