McKmeans: A highly efficient multi-core k-means algorithm for clustering extremely large datasets. McKmeans supports clustering gene expression, exon array, and SNP data sets.
Please also see our corresponding publication:
Kraus JM, Kestler HA. A highly efficient multi-core algorithm for clustering extremely large datasets. BMC Bioinform 11(1): 169, 2010. https://doi.org/10.1186/1471-2105-11-169