Medical Systems Biology

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Bioinformatics and Systems Biology (MolMed)

Coordinator: Prof. Dr. H. A. Kestler

Code: MOME.Ma1002

 


Announcement:

Lectures will start on October 23th

 

The post-exam review takes place on Friday, 09.02.2018 in O29, 2002 at 9:30-10:30.

 

Lectures:

Tuesday (14:30 - 16:00) Room O23, 2611 

Thursday (14:00 - 16:00) Room O23, 2611

 

Room changes:

Thursday, 26.10.2017 (16:00 - 18:00) O29, 2006

Tuesday, 07.11.2017 (14:00 - 16:00) seminar room surgical clinic 3.391 

Tuesday, 21.11.2017 (14:00 - 16:00) seminar room surgical clinic 3.391 

 

Excercises:

Thursday (16:00 - 18:00) Room O29, 3005/3006

Additional Exercise:

Thursday, 18.01.2018 (16:00-18:00) Room O29, 3005/3006

 

Exam:

Wednesday, 07.02.2018 (10:00 - 12:00) room: Hörsaal Chirurgie

 

Slides:

  1. Overview
  2. Signalling
  3. Epigenetics
  4. Omics: High throughput technologies
  5. Introduction to R
  6. Multivariate statistics
  7. Data Mining (1/2)
  8. Data Mining (2/2)
  9. Genomics
  10. NGS
  11. Mass spectrometry and Proteomics in Drug Discovery
  12. Bioinformatics in MS based qualitative and quantitative proteomics
  13. Sequence alignment and phylogenetic inference - Slides
  14. Sequence alignment and phylogenetic inference - Script
  15. Simulation and modeling
  16. Boolean networks (1/2)
  17. Boolean networks (2/2)
  18. Quantitative description of cellular processes


Exercise sheets:

  1. R basics
  2. Multivariate statistics and Data Mining
  3. NGS
  4. Proteomics
  5. Sequence alignment and phylogenetic inference
  6. Simulation and modeling
  7. Boolean networks
  8. Quantitative description of cellular processes

Additional material:

  1. Exercise 2: multivariate_statistics.RData
  2. Exercise 2: stc_dataset.RData
  3. Exercise 3: NGS Additional Material
  4. Exercise 4: MS/MS-Peaklists
  5. Exercise 6: data.mat.RData

Latest News

Our paper "A Boolean Network of the Crosstalk Between IGF and Wnt Signaling in Aging Satellite Cells" has been published in Plos One.

Our paper "Long-lived rodents reveal signatures of positive selection in genes associated with lifespan" has been published in Plos Genetics.