Medical Systems Biology

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Bioinformatics and Systems Biology (MolMed)

Coordinator: Prof. Dr. H. A. Kestler

Code: MOME.Ma1002

 


Announcement:

Lectures will start on October 23th


Lectures:

Tuesday (14:30 - 16:00) Room O23, 2611 

Thursday (14:00 - 16:00) Room O23, 2611

 

Room changes:

Thursday, 26.10.2017 (16:00 - 18:00) O29, 2006

Tuesday, 07.11.2017 (14:00 - 16:00) seminar room surgical clinic 3.391 

Tuesday, 21.11.2017 (14:00 - 16:00) seminar room surgical clinic 3.391 

 

Excercises:

Thursday (16:00 - 18:00) Room O29, 3005/3006

 

Exam:

Wednesday, 07.02.2018 (10:00 - 12:00) room: tba

 

Slides:

  1. Overview
  2. Signalling
  3. Epigenetics
  4. Omics: High throughput technologies
  5. Introduction to R
  6. Multivariate statistics
  7. Data Mining (1/2)
  8. Data Mining (2/2)
  9. Genomics
  10. NGS
  11. Mass spectrometry and Proteomics in Drug Discovery
  12. Bioinformatics in MS based qualitative and quantitative proteomics
  13. Sequence alignment and phylogenetic inference - Slides
  14. Sequence alignment and phylogenetic inference - Script
  15. Simulation and modeling
  16. Boolean networks (1/2)
  17. Boolean networks (2/2)


Exercise sheets:

  1. R basics
  2. Multivariate statistics and Data Mining
  3. NGS
  4. Proteomics
  5. Sequence alignment and phylogenetic inference
  6. Simulation and modeling
  7. Boolean networks

Additional material:

  1. Exercise 2: multivariate_statistics.RData
  2. Exercise 2: stc_dataset.RData
  3. Exercise 3: NGS Additional Material
  4. Exercise 4: MS/MS-Peaklists
  5. Exercise 6: data.mat.RData

Latest News

Our paper "A model of the onset of the Senescence Associated Secretory Phenotype after DNA damage induced Senescence" has been accepted for publishing in PLOS Computational Biology.

Our paper "The influence of multi-class feature selection on the prediction of diagnostic phenotypeshas been accepted for publishing in Neural Processing Letters.